CFPN Toxicology and Pharmacology in Forensic Cases 2

Question 1

A patient presents with miosis, respiratory depression, and altered mental status. Which drug class is most likely responsible?

Accepted Answer

Opioids

Answer

Stimulants

Answer

Benzodiazepines

Answer

Cannabis

Question 2

In postmortem forensic toxicology, which phenomenon can cause measured drug concentrations to differ from ante-mortem levels?

Accepted Answer

Postmortem redistribution

Answer

Livor mortis

Answer

Rigor mortis

Answer

Decomposition gases

Question 3

Which medication is a common antidote used in forensic/emergency settings to reverse opioid toxicity?

Accepted Answer

Naloxone

Answer

Flumazenil

Answer

N-acetylcysteine

Answer

Physostigmine

Question 4

What does a creatinine level below 2 mg/dL in a urine specimen indicate in forensic drug testing?

Accepted Answer

Specimen is not consistent with normal human urine (substituted)

Answer

Normal dilute specimen

Answer

High drug concentration expected

Answer

Specimen was properly collected

Question 5

Which class of drugs is detected using the EMIT immunoassay for THC metabolites in urine, and what is the standard federal cutoff concentration?

Accepted Answer

Cannabinoids at 50 ng/mL

Answer

Cannabinoids at 20 ng/mL

Answer

Cannabinoids at 100 ng/mL

Answer

Cannabinoids at 10 ng/mL

Question 6

Ethanol's primary route of metabolism involves which enzyme system?

Accepted Answer

Alcohol dehydrogenase (ADH)

Answer

Cytochrome P450 3A4 exclusively

Answer

Monoamine oxidase (MAO)

Answer

Glucuronyl transferase