CFC Toxicology & Drug Analysis 5

Question 1

Which phenomenon describes the increase in drug concentration within a specific organ or tissue relative to blood due to lipophilicity?

Accepted Answer

Bioaccumulation

Answer

Bioaccumulation (or tissue sequestration) occurs when lipophilic drugs concentrate in fatty tissues, leading to tissue-to-blood ratios greater than one.

Question 2

A forensic analyst tests a white powder using the Marquis reagent and observes a purple-to-black color change. This result is presumptive for:

Accepted Answer

Opiates (morphine/heroin)

Answer

The Marquis reagent turns purple-to-black in the presence of opiates such as morphine and heroin, serving as a presumptive color test.

Question 3

In alcohol pharmacokinetics, what is the average elimination rate of ethanol from blood in a non-tolerant individual?

Accepted Answer

0.015–0.02 g/dL per hour

Answer

Ethanol follows zero-order kinetics in most people, with average elimination rates of approximately 0.015–0.02 g/dL per hour in non-tolerant individuals.

Question 4

Which metabolite confirms that a person consumed heroin rather than prescribed morphine or codeine?

Accepted Answer

6-Monoacetylmorphine (6-MAM)

Answer

6-Monoacetylmorphine (6-MAM) is a unique heroin metabolite not produced from morphine or codeine, definitively confirming heroin use when detected.

Question 5

A suspect claims their positive cocaine urine test resulted from handling currency. As a forensic consultant, how should this be evaluated?

Accepted Answer

Reject the claim because passive transfer from handling cocaine-contaminated currency does not produce urine benzoylecgonine above cutoff levels

Answer

Scientific studies consistently show that passive handling of cocaine-contaminated currency does not produce urine benzoylecgonine concentrations at or above immunoassay cutoff levels (150 ng/mL).

(CFC) Certified Forensic Consultant Practice Test

(CFC) Certified Forensic Consultant Practice Test

CFC Toxicology & Drug Analysis 5