CETP Pharmaceutical Calculations 2

Question 1

A 72-year-old male weighs 80 kg and has a serum creatinine of 1.0 mg/dL. Using the Cockcroft-Gault equation [CrCl = (140 − age) × weight ÷ (72 × SCr)], what is his estimated creatinine clearance?

Accepted Answer

75 mL/min

Answer

(140 − 72) × 80 ÷ (72 × 1.0) = 68 × 80 ÷ 72 ≈ 75.6 mL/min.

Question 2

How many milliequivalents (mEq) of potassium chloride are contained in 30 mL of a 2 mEq/mL solution?

Accepted Answer

60 mEq

Answer

2 mEq/mL × 30 mL = 60 mEq of potassium chloride.

Question 3

Using the alligation method, what volumes of 70% alcohol and 30% alcohol are needed to prepare 500 mL of 50% alcohol?

Accepted Answer

250 mL of 70% and 250 mL of 30%

Answer

Parts of 70% = 50 − 30 = 20; parts of 30% = 70 − 50 = 20; equal ratio = 250 mL each.

Question 4

A pediatric patient has a body surface area (BSA) of 0.5 m². The adult dose of a medication is 200 mg. Using the BSA method (Pediatric dose = [Child BSA ÷ 1.73 m²] × Adult dose), what is the appropriate pediatric dose?

Accepted Answer

58 mg

Answer

(0.5 ÷ 1.73) × 200 mg = 0.289 × 200 ≈ 58 mg.

Question 5

An IV infusion is ordered at 30 drops/min using a 20 drops/mL administration set. What is the equivalent infusion rate in mL/hr?

Accepted Answer

90 mL/hr

Answer

30 drops/min ÷ 20 drops/mL = 1.5 mL/min × 60 min/hr = 90 mL/hr.

Canadian Entry To Practice

Canadian Entry To Practice

CETP Pharmaceutical Calculations 2