CETP CETP Sterile Preparations 2 — Questions and Answers
Question 1: What is the minimum garbing requirement before entering an ISO Class 5 sterile compounding area?
- Gloves only
- Gown and gloves only
- Gown, gloves, and hair cover only
- Gown, gloves, hair cover, face mask, and shoe covers (Correct answer)
Correct answer: Gown, gloves, hair cover, face mask, and shoe covers
Complete garbing including gown, gloves, hair cover, face mask, and shoe covers is required to minimize particle introduction into the clean room.
Question 2: Which solution is the standard disinfectant used to clean surfaces in sterile compounding areas?
- Distilled water
- Isopropyl alcohol 70% (Correct answer)
- Hydrogen peroxide 30%
- Sodium chloride 0.9%
Correct answer: Isopropyl alcohol 70%
Isopropyl alcohol 70% is the standard disinfectant for sterile compounding surfaces because its water content aids protein denaturation in microorganisms.
Question 3: What is the correct technique when withdrawing medication from a vial using a needle and syringe?
- Insert the needle and withdraw without injecting air first
- Inject air equal to the volume to be withdrawn, then withdraw the medication (Correct answer)
- Insert the needle at a 45-degree angle without adding air
- Pre-fill the syringe with sterile water before inserting into the vial
Correct answer: Inject air equal to the volume to be withdrawn, then withdraw the medication
Injecting air equal to the desired withdrawal volume creates positive pressure inside the vial, facilitating smooth and accurate medication withdrawal.
Question 4: Which filter pore size is used to sterilize solutions that cannot be heat-sterilized?
- 5.0-micron filter
- 10-micron filter
- 0.22-micron filter (Correct answer)
- 0.45-micron filter
Correct answer: 0.22-micron filter
A 0.22-micron filter removes bacteria and fungi and is the accepted standard for sterilizing heat-sensitive solutions by filtration.
Question 5: What is a compounding aseptic containment isolator (CACI) primarily used for?
- Refrigerating prepared sterile products
- Preparing hazardous sterile drugs in a closed, protective environment (Correct answer)
- Testing the sterility of compounded products
- Disposing of contaminated sharps safely
Correct answer: Preparing hazardous sterile drugs in a closed, protective environment
A CACI is an enclosed negative-pressure device that protects both the compounder and the product when preparing hazardous sterile medications such as chemotherapy agents.
Question 6: How should unused portions of single-dose vials (SDVs) be handled after initial use?
- Store in the refrigerator for up to 7 days
- Pool with other patients' vials to minimize waste
- Discard immediately after use without saving (Correct answer)
- Use within 24 hours if stored in the LAFW
Correct answer: Discard immediately after use without saving
Single-dose vials contain no antimicrobial preservatives and must be discarded immediately after use to prevent microbial contamination and cross-patient infection.
CETP CETP Sterile Preparations 2
What is the minimum garbing requirement before entering an ISO Class 5 sterile compounding area?