Certified Gastroenterology RN Gastroenterology Pharmacology 5

Question 1

A patient beginning quadruple therapy for H. pylori with bismuth, metronidazole, tetracycline, and a PPI must avoid which substance?

Accepted Answer

Alcohol

Answer

Metronidazole with alcohol can cause a disulfiram-like reaction with flushing, vomiting, and tachycardia.

Question 2

Which finding indicates a therapeutic response to lactulose in hepatic encephalopathy?

Accepted Answer

Improved mental status and decreased serum ammonia

Answer

Effective lactulose therapy lowers ammonia levels, which correlates with improved level of consciousness.

Question 3

A patient on high-dose loperamide abuse is at risk for which cardiac complication?

Accepted Answer

QT prolongation and torsades de pointes

Answer

Supratherapeutic loperamide blocks cardiac potassium channels, causing QT prolongation and life-threatening arrhythmias.

Question 4

Which baseline test is required before starting a patient on infliximab?

Accepted Answer

Tuberculosis screening

Answer

Anti-TNF therapy can reactivate latent tuberculosis, so TB screening is mandatory before initiation.

Question 5

Ursodiol is prescribed for a patient primarily to achieve which therapeutic effect?

Accepted Answer

Dissolution of cholesterol gallstones

Answer

Ursodiol reduces biliary cholesterol saturation, gradually dissolving small non-calcified cholesterol gallstones.

Certified Gastroenterology RN Practice Test