CDT Wound Care & Healing 2 — Questions and Answers
Question 1: Which growth factor is most critical for stimulating fibroblast proliferation during the proliferative phase of wound healing?
- Platelet-derived growth factor (PDGF) (Correct answer)
- Tumor necrosis factor-alpha (TNF-α)
- Interleukin-6 (IL-6)
- Complement factor C3
Correct answer: Platelet-derived growth factor (PDGF)
PDGF is released from platelets and macrophages and is a primary chemotactic and mitogenic signal for fibroblasts during the proliferative phase.
Question 2: A wound with yellow, stringy tissue adhering to the wound bed is described as containing which type of tissue?
- Granulation tissue
- Slough (Correct answer)
- Eschar
- Epithelium
Correct answer: Slough
Slough is devitalized, moist, yellow or tan stringy tissue that must be debrided to facilitate wound healing.
Question 3: Which dressing type creates a moist wound environment while being appropriate for a heavily exudating wound?
- Hydrocolloid
- Transparent film
- Alginate (Correct answer)
- Hydrogel
Correct answer: Alginate
Alginate dressings are highly absorbent and derived from seaweed, making them ideal for heavily exudating wounds.
Question 4: In which phase of wound healing does angiogenesis primarily occur?
- Hemostasis
- Inflammatory
- Proliferative (Correct answer)
- Remodeling
Correct answer: Proliferative
Angiogenesis, the formation of new blood vessels, occurs primarily during the proliferative phase to support the growing granulation tissue.
Question 5: A patient has a wound that has been open for 10 weeks with no signs of healing progression. This is classified as:
- Acute wound
- Chronic wound (Correct answer)
- Traumatic wound
- Surgical wound
Correct answer: Chronic wound
A wound that fails to progress through normal healing stages within 4–6 weeks is classified as a chronic wound.
Question 6: Which bacteria is most commonly associated with biofilm formation that impedes chronic wound healing?
- Staphylococcus aureus (Correct answer)
- Streptococcus pyogenes
- Clostridium perfringens
- Haemophilus influenzae
Correct answer: Staphylococcus aureus
Staphylococcus aureus, including MRSA strains, is the most prevalent organism found in chronic wound biofilms.
Question 7: The TIME wound bed preparation framework stands for Tissue, Infection/Inflammation, Moisture imbalance, and:
- Temperature elevation
- Edge of wound/Epithelial advancement (Correct answer)
- Tissue oxygenation
- Topical antibiotic application
Correct answer: Edge of wound/Epithelial advancement
The 'E' in TIME refers to Edge of wound/Epithelial advancement, assessing whether wound edges are progressing and epithelializing.
CDT Wound Care & Healing 2
Which growth factor is most critical for stimulating fibroblast proliferation during the proliferative phase of wound healing?