CDCES Pharmacology Fundamentals 4

Question 1

A patient using insulin pump therapy (CSII) experiences a site infection. What education should the CDCES provide?

Accepted Answer

Rotate sites every 3-7 days and inspect sites at each change

Answer

Keep the same site for 2 weeks to allow healing

Answer

Only use abdominal sites with CSII

Answer

Antibiotics are always required for site infections

Question 2

Which sulfonylurea is preferred in elderly patients due to its lower risk of prolonged hypoglycemia?

Accepted Answer

Glipizide

Answer

Glyburide

Answer

Chlorpropamide

Answer

Glimepiride

Question 3

A patient with type 2 diabetes and chronic kidney disease (eGFR 25) needs glucose-lowering therapy. Which agent requires the most caution?

Accepted Answer

Metformin

Answer

Linagliptin

Answer

Insulin glargine

Answer

Empagliflozin

Question 4

What is the primary mechanism by which GLP-1 receptor agonists promote weight loss?

Accepted Answer

Slowing gastric emptying and reducing appetite via central hypothalamic effects

Answer

Increasing metabolic rate through thermogenesis

Answer

Increasing urinary calorie excretion

Answer

Blocking fat absorption in the intestine

Question 5

A patient reports that their insulin pen was left at room temperature for 28 days. What should the CDCES advise?

Accepted Answer

Discard the pen as most insulins are only stable for 28 days at room temperature

Answer

The insulin is still effective if it appears clear

Answer

Refrigerate the pen immediately to restore potency

Answer

Test glucose more frequently but continue using the insulin

Question 6

Colesevelam (a bile acid sequestrant) has an FDA-approved indication for which condition beyond cholesterol lowering?

Accepted Answer

Type 2 diabetes as an adjunct to diet and exercise

Answer

Type 1 diabetes as add-on therapy

Answer

Gestational diabetes management

Answer

Prediabetes prevention

Question 7

Which insulin storage instruction is most important to prevent degradation?

Accepted Answer

Never freeze insulin or expose to extreme heat above 86°F (30°C)

Answer

Always shake the vial vigorously before use

Answer

Store all insulin at room temperature permanently

Answer

Keep insulin in direct sunlight for easier visual inspection