Pharmacology & Medication Management Flashcards
7 cards from real CDC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Pharmacology & Medication Management flashcards as text
A patient taking metformin requires IV contrast for imaging. Which dental sedation drug class requires the most caution due to lactic acidosis risk when combined with contrast?
Answer: Benzodiazepines
While metformin-contrast interaction is the primary concern, benzodiazepines used in sedation can mask early lactic acidosis symptoms, complicating monitoring.
What is the reversal agent for benzodiazepine-induced respiratory depression in dental sedation emergencies?
Answer: Flumazenil
Flumazenil is a competitive benzodiazepine receptor antagonist that rapidly reverses sedation and respiratory depression caused by benzodiazepines.
Which drug is used to manage methemoglobinemia caused by excessive prilocaine administration?
Answer: Methylene blue
Methylene blue reduces methemoglobin back to functional hemoglobin by acting as an electron donor in the NADPH pathway.
A patient on chronic corticosteroid therapy requires oral surgery. Which perioperative management concern is MOST relevant?
Answer: Adrenal insufficiency
Chronic corticosteroid use suppresses the HPA axis, placing patients at risk for adrenal crisis under surgical stress; steroid supplementation may be needed.
Which antifungal drug used to treat oral candidiasis is known to significantly inhibit CYP3A4 and increase levels of many co-administered drugs?
Answer: Fluconazole
Fluconazole is a potent CYP3A4 inhibitor that can markedly elevate plasma concentrations of drugs like warfarin, benzodiazepines, and statins.
What is the maximum safe daily dose of acetaminophen for a healthy adult patient to avoid hepatotoxicity?
Answer: 4,000 mg
The FDA recommends a maximum daily dose of 4,000 mg acetaminophen for healthy adults, though 3,000 mg is preferred for elderly or at-risk patients.
Which local anesthetic is CONTRAINDICATED in patients with a hereditary condition causing abnormal plasma cholinesterase (pseudocholinesterase deficiency)?
Answer: Benzocaine
Benzocaine is an ester-type local anesthetic metabolized by plasma cholinesterase; patients with pseudocholinesterase deficiency cannot break it down effectively, leading to toxicity.