Organ Procurement and Preservation Flashcards
7 cards from real CCTC practice questions. Tap to flip, then mark Knew It or Still Learning โ missed cards come back until you master them.
Read the first 7 Organ Procurement and Preservation flashcards as text
Which preservation solution is most commonly used for pancreas preservation due to its high viscosity and oncotic properties?
Answer: University of Wisconsin (UW) solution
UW solution contains hydroxyethyl starch which provides oncotic support and is the gold standard for pancreas preservation, allowing up to 30 hours of cold ischemia.
During back-table preparation of a donor kidney, the transplant coordinator notices the renal artery has an accessory lower pole artery. What is the appropriate action?
Answer: Document and report the finding to the surgical team for reconstruction planning
Accessory renal arteries must be documented and communicated to the surgical team so they can plan appropriate reconstruction to ensure adequate blood supply to all segments of the kidney.
What is the primary purpose of pulsatile machine perfusion (PMP) compared to static cold storage for kidneys?
Answer: It provides continuous flow that may reduce delayed graft function and allows viability assessment
Pulsatile machine perfusion maintains continuous flow mimicking physiologic conditions, which may reduce ischemia-reperfusion injury and allows real-time monitoring of renal resistance and flow as viability markers.
A donor is declared brain dead and consent is obtained. Before organ procurement, the coordinator notes the donor's creatinine has risen from 0.9 to 2.8 mg/dL over 24 hours. What is the best course of action?
Answer: Notify the transplanting surgeon and OPO medical director to evaluate the clinical context
Rising creatinine in brain-dead donors is common due to hemodynamic instability and requires clinical context evaluation; the decision to accept or decline organs rests with the transplanting surgeon in collaboration with the OPO medical director.
What is the maximum recommended cold ischemia time for a donor liver to minimize primary non-function risk?
Answer: 12 hours
Liver cold ischemia time should ideally be kept under 12 hours, as times exceeding this threshold significantly increase the risk of primary non-function and ischemic cholangiopathy.
Which technique is used to assess the viability of a marginal donor liver prior to transplantation using a normothermic circuit?
Answer: Normothermic regional perfusion (NRP) or normothermic machine perfusion (NMP)
Normothermic machine perfusion restores near-physiologic conditions allowing the liver to produce bile and metabolize lactate, providing functional viability assessment not possible with static cold storage.
Under UNOS/OPTN policy, which circumstance requires a coordinator to notify the potential recipient center of a change in donor status during procurement?
Answer: Any significant change in donor clinical status, serology results, or organ quality discovered during procurement
UNOS/OPTN policy mandates timely communication of any significant change in donor information that could affect organ suitability or recipient risk to all accepting transplant programs.