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Evaluation and Preparation for Transplant Flashcards

7 cards from real CCTC practice questions. Tap to flip, then mark Knew It or Still Learning โ€” missed cards come back until you master them.

Read the first 7 Evaluation and Preparation for Transplant flashcards as text
  1. Which scoring system is used to assess disease severity and waitlist priority for patients with primary biliary cholangitis awaiting liver transplant?

    Answer: MELD or MELD-Na

    MELD or MELD-Na is the standard UNOS allocation tool used for all chronic liver disease etiologies including primary biliary cholangitis.

  2. A renal transplant candidate has a BMI of 42. What is the primary concern at most transplant centers regarding listing this patient?

    Answer: Increased risk of wound complications, delayed graft function, and reduced graft survival

    Morbid obesity (BMI >40) is associated with higher surgical complication rates, wound dehiscence, delayed graft function, and worse long-term graft survival.

  3. During evaluation, a liver transplant candidate is found to have hepatopulmonary syndrome (HPS). How does this affect their transplant candidacy?

    Answer: Severe HPS may qualify the patient for MELD exception points and HPS typically reverses post-transplant

    HPS is a complication of portal hypertension that typically reverses after liver transplant; severe HPS (PaO2 <60 mmHg) can qualify patients for exception MELD points.

  4. What is the significance of elevated panel reactive antibody (PRA) levels greater than 80% in a kidney transplant candidate?

    Answer: The patient is highly sensitized, limiting compatible donors and increasing rejection risk

    PRA >80% indicates high sensitization, meaning fewer compatible donors are available and the risk of antibody-mediated rejection is significantly elevated.

  5. A candidate being evaluated for heart transplant has significant, unresolved pulmonary hypertension with transpulmonary gradient >15 mmHg. What is the most likely outcome of this finding?

    Answer: Deferral pending optimization; severe fixed pulmonary hypertension contraindicates transplant due to right heart failure risk

    Fixed pulmonary hypertension causes acute right ventricular failure in the donor heart; candidates must undergo vasodilator challenge to determine reversibility before listing.

  6. Which condition defines portopulmonary hypertension (POPH), and how does it affect liver transplant candidacy?

    Answer: POPH is pulmonary arterial hypertension in the setting of portal hypertension; moderate cases may be bridged to transplant with vasodilator therapy

    POPH is pulmonary arterial hypertension complicating portal hypertension; moderate POPH responsive to vasodilator therapy can be bridged to transplant, while severe unresponsive POPH is a contraindication.

  7. Which specialist is most important to include in the multidisciplinary transplant evaluation team when a candidate has poorly controlled diabetes?

    Answer: Endocrinologist

    An endocrinologist optimizes glycemic control pre- and post-transplant, as immunosuppressive medications like steroids significantly worsen diabetes after transplant.