Evaluation and Preparation for Transplant Flashcards
7 cards from real CCTC practice questions. Tap to flip, then mark Knew It or Still Learning โ missed cards come back until you master them.
Read the first 7 Evaluation and Preparation for Transplant flashcards as text
Which scoring system is used to assess disease severity and waitlist priority for patients with primary biliary cholangitis awaiting liver transplant?
Answer: MELD or MELD-Na
MELD or MELD-Na is the standard UNOS allocation tool used for all chronic liver disease etiologies including primary biliary cholangitis.
A renal transplant candidate has a BMI of 42. What is the primary concern at most transplant centers regarding listing this patient?
Answer: Increased risk of wound complications, delayed graft function, and reduced graft survival
Morbid obesity (BMI >40) is associated with higher surgical complication rates, wound dehiscence, delayed graft function, and worse long-term graft survival.
During evaluation, a liver transplant candidate is found to have hepatopulmonary syndrome (HPS). How does this affect their transplant candidacy?
Answer: Severe HPS may qualify the patient for MELD exception points and HPS typically reverses post-transplant
HPS is a complication of portal hypertension that typically reverses after liver transplant; severe HPS (PaO2 <60 mmHg) can qualify patients for exception MELD points.
What is the significance of elevated panel reactive antibody (PRA) levels greater than 80% in a kidney transplant candidate?
Answer: The patient is highly sensitized, limiting compatible donors and increasing rejection risk
PRA >80% indicates high sensitization, meaning fewer compatible donors are available and the risk of antibody-mediated rejection is significantly elevated.
A candidate being evaluated for heart transplant has significant, unresolved pulmonary hypertension with transpulmonary gradient >15 mmHg. What is the most likely outcome of this finding?
Answer: Deferral pending optimization; severe fixed pulmonary hypertension contraindicates transplant due to right heart failure risk
Fixed pulmonary hypertension causes acute right ventricular failure in the donor heart; candidates must undergo vasodilator challenge to determine reversibility before listing.
Which condition defines portopulmonary hypertension (POPH), and how does it affect liver transplant candidacy?
Answer: POPH is pulmonary arterial hypertension in the setting of portal hypertension; moderate cases may be bridged to transplant with vasodilator therapy
POPH is pulmonary arterial hypertension complicating portal hypertension; moderate POPH responsive to vasodilator therapy can be bridged to transplant, while severe unresponsive POPH is a contraindication.
Which specialist is most important to include in the multidisciplinary transplant evaluation team when a candidate has poorly controlled diabetes?
Answer: Endocrinologist
An endocrinologist optimizes glycemic control pre- and post-transplant, as immunosuppressive medications like steroids significantly worsen diabetes after transplant.