CCS Hemostasis and Coagulation Management 2

Question 1

Which blood product is most appropriate to correct dilutional thrombocytopenia causing microvascular bleeding after cardiopulmonary bypass?

Accepted Answer

Platelet transfusion

Answer

Fresh frozen plasma

Answer

Cryoprecipitate

Answer

Packed red blood cells

Question 2

Cryoprecipitate is the preferred product for replacing which coagulation factor in a cardiac surgery patient with significant bleeding?

Accepted Answer

Factor VIII and fibrinogen

Answer

Factor IX and protein C

Answer

Factor VII and protein S

Answer

Factors II, VII, IX, and X

Question 3

What minimum platelet count is generally recommended before performing cardiac surgery to reduce perioperative bleeding risk?

Accepted Answer

100,000/µL

Answer

20,000/µL

Answer

50,000/µL

Answer

150,000/µL

Question 4

Which antifibrinolytic agent is most commonly used in cardiac surgery to reduce perioperative blood loss?

Accepted Answer

Tranexamic acid

Answer

Aminocaproic acid

Answer

Aprotinin

Answer

Desmopressin (DDAVP)

Question 5

A patient develops excessive bleeding after protamine reversal of heparin following CPB, with a normal ACT. Thromboelastography shows decreased clot amplitude. Which intervention is most appropriate?

Accepted Answer

Administer platelet transfusion

Answer

Administer additional protamine

Answer

Transfuse fresh frozen plasma

Answer

Give recombinant factor VIIa

Question 6

Which laboratory finding is most consistent with disseminated intravascular coagulation (DIC) in a post-cardiac surgery patient?

Accepted Answer

Low fibrinogen, prolonged PT/aPTT, elevated D-dimer, thrombocytopenia

Answer

Elevated fibrinogen, prolonged PT, thrombocytopenia

Answer

Normal PT, elevated fibrinogen, thrombocytosis

Answer

Low D-dimer, normal PT, elevated fibrinogen

Question 7

Desmopressin (DDAVP) is used perioperatively in cardiac surgery primarily to treat bleeding associated with which condition?

Accepted Answer

Platelet dysfunction due to aspirin or uremia

Answer

Heparin overdose

Answer

Warfarin toxicity

Answer

Factor VIII deficiency (hemophilia A)