CCRC Study Guide 2026
Everything you need to pass the CCRC exam in one place: the exam format, every topic to study, real practice questions with explanations, flashcards, and full-length practice tests. Free, no sign-up needed.
📋 CCRC Exam Format at a Glance
📚 CCRC Topics to Study (21)
✍️ Sample CCRC Questions & Answers
1. What is the purpose of a Delegation of Authority (DoA) log in a clinical trial?
The DoA log documents that the PI has formally assigned specific trial tasks to qualified, trained staff members and is a key GCP requirement.
2. What is the purpose of a Corrective and Preventive Action (CAPA) plan submitted to a sponsor after a monitoring finding?
A CAPA plan identifies the root cause of a finding and details specific steps to correct the problem and prevent it from happening again.
3. A subject is issued 120 tablets and is instructed to take 2 tablets 4 times a day. He returns 88 tablets on the morning of day 9 fasting for laboratory tests. What percent compliant is he?
If 92 bottles are available for the CRC to return from an initial supply of 100 bottles, it means that 8 bottles were ultimately not returned (100 - 92 = 8). This implies that despite 26 subjects being enrolled and each receiving two bottles (52 bottles dispensed), only 8 bottles were consumed or otherwise unaccounted for, with the remaining dispensed bottles being returned unused.
4. A participant received a study drug dose 20% higher than specified in the protocol due to a calculation error. This event is BEST classified as:
An incorrect dosing error is a protocol deviation (and likely a major one) that must be documented and reported to the sponsor and potentially the IRB.
5. If a sponsor places a study on clinical hold, what must the site immediately do?
A clinical hold requires the site to immediately suspend enrollment and interventions as directed by the sponsor pending FDA resolution of the safety concern.
6. What is one way a Clinical Research Coordinator can increase their salary potential?
Increasing salary potential for a Clinical Research Coordinator involves a multi-faceted approach. Gaining additional experience, especially in complex trials or leadership roles, directly enhances market value. Obtaining advanced certifications, such as the CCRC, demonstrates specialized knowledge and commitment, while pursuing further education like a Master's degree can open doors to higher-level positions and increased earning capacity.