During a monitoring visit, the CRA finds that the investigator site file (ISF) is missing the latest protocol amendment signed by the PI. What action should the CRA take?
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A
Document the missing document as a finding and request that the site obtain and file it promptly
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B
Immediately terminate the site from the study
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C
Ignore the issue if the PI verbally confirms awareness of the amendment
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D
File the document on behalf of the site without notifying the sponsor