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Polypharmacy & Medication Reconciliation Flashcards

7 cards from real CCP practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A chronic care professional is educating a patient about medication adherence barriers. Which barrier is MOST commonly reported by patients with polypharmacy?

    Answer: Complexity of medication regimen

    Regimen complexity — multiple medications, different frequencies, and special instructions — is the most commonly reported adherence barrier in polypharmacy patients.

  2. A patient on digoxin is started on clarithromycin for a respiratory infection. Which monitoring parameter is most critical?

    Answer: Digoxin serum levels and signs of toxicity

    Clarithromycin inhibits P-glycoprotein and CYP3A4, reducing digoxin clearance and raising serum digoxin to potentially toxic levels.

  3. Which of the following interventions has the strongest evidence for reducing medication-related adverse events at hospital discharge?

    Answer: Pharmacist-led medication reconciliation and patient counseling

    Pharmacist-led reconciliation combined with patient counseling at discharge has the strongest evidence for preventing medication errors and adverse drug events.

  4. A care manager identifies that a patient with hypertension and gout is taking hydrochlorothiazide. Which drug-disease concern should be flagged?

    Answer: Thiazides raise uric acid levels and can precipitate gout attacks

    Thiazide diuretics increase serum uric acid reabsorption and can trigger gout flares, making them a drug-disease interaction concern in gout patients.

  5. Which of the following statements about the Medication Appropriateness Index (MAI) is correct?

    Answer: MAI evaluates 10 criteria per medication including indication, efficacy, and cost

    The MAI uses 10 explicit criteria per medication — including indication, effectiveness, dosage, directions, interactions, and cost — to rate appropriateness.

  6. A patient reports skipping her blood pressure medications because she cannot afford them. Which role does the chronic care professional play in this situation?

    Answer: Identify patient assistance programs and communicate cost barriers to the prescriber

    Care professionals address cost barriers by connecting patients with assistance programs and collaborating with prescribers to explore affordable alternatives.

  7. Which patient population has the highest risk for clinically significant drug interactions due to altered pharmacokinetics associated with aging?

    Answer: Adults aged 65+ with multiple chronic conditions on polypharmacy

    Older adults with multiple chronic conditions on polypharmacy have the highest risk due to age-related declines in hepatic metabolism, renal clearance, and body composition changes.