CCP CCP Blood Conservation & Transfusion Strategies 3

Question 1

Fresh frozen plasma (FFP) is indicated post-CPB when:

Accepted Answer

PT/INR is significantly elevated with active microvascular bleeding

Answer

Hemoglobin falls below 8 g/dL

Answer

Platelet count drops below 100,000/µL

Answer

ACT exceeds 400 seconds after protamine

Question 2

Cryoprecipitate is administered post-bypass primarily to replace:

Accepted Answer

Fibrinogen and factor VIII

Answer

Factor IX deficiency

Answer

Platelets in thrombocytopenic patients

Answer

Albumin for oncotic pressure

Question 3

Preoperative autologous donation (PAD) for elective cardiac surgery is currently:

Accepted Answer

Largely abandoned due to evidence of preoperative anemia induction with no clear benefit

Answer

Standard of care for all elective cardiac cases

Answer

Mandatory for Jehovah's Witness patients prior to surgery

Answer

Routinely used only in pediatric cardiac surgery

Question 4

Acute normovolemic hemodilution (ANH) works by:

Accepted Answer

Collecting whole blood at surgery start, replacing volume with crystalloid/colloid, then retransfusing after bypass

Answer

Filtering plasma from blood during bypass to remove water

Answer

Adding isotonic saline to the CPB prime to dilute the blood

Answer

Rapidly warming stored allogeneic blood before administration

Question 5

Point-of-care platelet function testing using devices such as the Multiplate analyzer helps guide:

Accepted Answer

Targeted platelet transfusion decisions in coagulopathic patients

Answer

ACT-based heparin management during bypass

Answer

Heparin dose-response curve calculations

Answer

Temperature management during the rewarming phase

Question 6

Protamine administration after CPB can cause which of the following serious adverse effects?

Accepted Answer

Systemic hypotension and pulmonary hypertension

Answer

Thrombocytosis and hypercoagulability

Answer

Metabolic alkalosis

Answer

Increased systemic fibrinolysis