CCP CCP Blood Conservation & Transfusion Strategies 2

Question 1

Conventional ultrafiltration (CUF) performed during CPB is used to:

Accepted Answer

Remove excess fluid and hemoconcentrate the patient during bypass

Answer

CUF removes excess water and small solutes across a semipermeable membrane during CPB, helping manage volume balance and hemoconcentrate the patient.

Question 2

Which coagulation factor is most rapidly depleted during CPB due to hemodilution and consumption?

Accepted Answer

Fibrinogen

Answer

Fibrinogen is highly susceptible to dilutional loss and CPB-induced consumption, and its depletion is a major contributor to post-bypass coagulopathy.

Question 3

Platelet dysfunction after CPB is primarily caused by:

Accepted Answer

Platelet activation and degranulation from contact with CPB circuit surfaces

Answer

Contact of platelets with the artificial surfaces of the CPB circuit causes activation, degranulation, and a qualitative functional defect even when platelet counts remain adequate.

Question 4

Desmopressin (DDAVP) is used in cardiac surgery primarily to:

Accepted Answer

Release endogenous von Willebrand factor and factor VIII to improve platelet function

Answer

DDAVP stimulates endothelial release of stored von Willebrand factor and factor VIII, improving platelet adhesion especially in patients with qualitative platelet dysfunction.

Question 5

A bloodless surgery program for Jehovah's Witness patients primarily relies on:

Accepted Answer

Preoperative optimization, cell salvage, and volume expanders to avoid allogeneic transfusion

Answer

Bloodless surgery programs combine preoperative erythropoietin/iron therapy, intraoperative cell salvage, meticulous hemostasis, and volume expanders to avoid all allogeneic blood products.

(CCP) Certified Clinical Perfusionist Practice Test

(CCP) Certified Clinical Perfusionist Practice Test

CCP CCP Blood Conservation & Transfusion Strategies 2