Practice Test Geeks(CCDM) Certified Clinical Data Manager Practice Test
← All CCDM Flashcard Decks

Statistical Analysis Flashcards

7 cards from real CCDM practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Statistical Analysis flashcards as text

  1. In a clinical trial, a p-value of 0.03 is obtained. Which statement is most accurate?

    Answer: There is a 3% chance of observing results as extreme as these if the null hypothesis is true

    A p-value represents the probability of obtaining results at least as extreme as observed, assuming the null hypothesis is true.

  2. Which type of analysis includes all randomized patients in their originally assigned treatment groups, regardless of protocol adherence?

    Answer: Intention-to-treat analysis

    Intention-to-treat (ITT) analysis includes all randomized subjects analyzed in their assigned groups, preserving randomization balance.

  3. A 95% confidence interval for a mean difference is (2.1, 8.4). What does this indicate?

    Answer: We are 95% confident the true population parameter lies within this interval

    A confidence interval means that 95% of similarly constructed intervals from repeated sampling would contain the true population parameter.

  4. When is a Kaplan-Meier curve the most appropriate analytical tool?

    Answer: Analyzing time-to-event data with censored observations

    Kaplan-Meier curves are used to estimate survival functions from time-to-event data that includes censored observations.

  5. What does a hazard ratio of 0.70 indicate in a survival analysis?

    Answer: The treatment group has a 30% lower risk of the event at any point in time

    A hazard ratio of 0.70 means the treatment group experiences the event at 70% the rate of the control group, a 30% relative reduction.

  6. Which statistical method is used to adjust for multiple baseline covariates simultaneously while estimating a treatment effect?

    Answer: Analysis of covariance (ANCOVA)

    ANCOVA adjusts for baseline covariates to reduce residual variance and provide a more precise estimate of the treatment effect.

  7. In a crossover trial, what statistical test is most appropriate when comparing two continuous outcomes with normally distributed data?

    Answer: Paired t-test

    In crossover designs, the same subjects receive both treatments, making paired analyses appropriate to account for within-subject correlation.