CCAP Pharmacology Fundamentals 3

Question 1

When two essential oil constituents work together to produce an effect greater than the sum of their individual effects, this is called:

Accepted Answer

Synergism

Answer

Synergism occurs when the combined pharmacological effect of two or more constituents exceeds what each would produce independently.

Question 2

The blood-brain barrier (BBB) presents a challenge for some essential oil constituents because it:

Accepted Answer

Restricts passage of highly water-soluble or large molecules

Answer

The BBB restricts passage of hydrophilic, large, or ionized molecules, while small lipophilic essential oil constituents can cross relatively easily.

Question 3

Which essential oil constituent class is most associated with inhibiting acetylcholinesterase, relevant to potential interactions with Alzheimer's medications?

Accepted Answer

Sesquiterpene lactones

Answer

Sesquiterpene lactones from plants like yarrow have demonstrated acetylcholinesterase inhibitory activity, which may interact with cholinesterase-inhibiting drugs used in dementia.

Question 4

A practitioner recommends bergamot oil to a client taking a statin drug. The primary concern should be that bergamot constituents may:

Accepted Answer

Inhibit CYP3A4, raising statin plasma levels and risk of myopathy

Answer

Bergamot furanocoumarin-free fractions and certain components can inhibit CYP3A4, the main enzyme metabolizing many statins, potentially causing dangerous drug accumulation.

Question 5

The concept of a 'therapeutic window' in pharmacology means:

Accepted Answer

The range between the minimum effective dose and the toxic dose

Answer

The therapeutic window is the dose range in which a substance produces its desired effect without causing unacceptable toxicity.

(CCAP) Certified Clinical Aromatherapy Practitioner Practice Test

(CCAP) Certified Clinical Aromatherapy Practitioner Practice Test

CCAP Pharmacology Fundamentals 3