CBRN Pharmacology & Medication Management 2

Question 1

Ketamine is frequently chosen for burn wound care procedures because it provides:

Accepted Answer

Dissociative anesthesia with preservation of airway reflexes and hemodynamic stability

Answer

Muscle paralysis with minimal sedation

Answer

Deep sedation without analgesic properties

Answer

Local anesthesia confined to the wound site

Question 2

In a burn patient receiving systemic antibiotics, which physiological factor most significantly alters drug pharmacokinetics compared to non-burn patients?

Accepted Answer

Increased volume of distribution due to massive fluid shifts and edema

Answer

Decreased gastric motility reducing oral absorption

Answer

Reduced hepatic metabolism from burn-related liver damage

Answer

Increased protein binding due to elevated acute-phase proteins

Question 3

Oxandrolone (an anabolic steroid) is used in severe burn patients primarily to:

Accepted Answer

Counteract catabolism and preserve lean body mass

Answer

Decrease wound infection rates through immune modulation

Answer

Enhance procedural pain control

Answer

Reduce hypertrophic scar formation

Question 4

Which topical burn wound agent is CONTRAINDICATED in a patient with a documented sulfonamide allergy?

Accepted Answer

Silver sulfadiazine (Silvadene)

Answer

Silver nitrate solution

Answer

Bacitracin ointment

Answer

Petroleum-based gauze dressings

Question 5

Benzodiazepines and/or melatonin are used in burn ICU patients primarily to address:

Accepted Answer

ICU-related anxiety, sleep disturbances, and delirium prevention

Answer

Wound infection prevention through immune enhancement

Answer

Reduction of the hypermetabolic rate

Answer

Prevention of deep vein thrombosis

Question 6

Recombinant human growth hormone (rhGH) has been studied in pediatric burn patients to:

Accepted Answer

Accelerate wound healing and reduce hospital length of stay

Answer

Prevent wound infections by enhancing immune response

Answer

Control pain during dressing changes

Answer

Prevent hypertrophic scarring post-healing

Question 7

Which anticoagulation strategy is most commonly used in burn patients for deep vein thrombosis (DVT) prophylaxis?

Accepted Answer

Low molecular weight heparin (LMWH) such as enoxaparin

Answer

Warfarin with daily INR monitoring

Answer

Aspirin 325 mg daily alone

Answer

Direct oral anticoagulants like rivaroxaban