CARN Pharmacology & Substance Use Disorders 2

Question 1

A patient on methadone maintenance therapy reports QTc prolongation on ECG. What is the most appropriate nursing action?

Accepted Answer

Notify the prescriber and monitor for arrhythmias

Answer

Discontinue methadone immediately

Answer

Administer a beta-blocker

Answer

Increase the methadone dose gradually

Question 2

Which benzodiazepine is preferred for alcohol withdrawal management in patients with severe liver disease?

Accepted Answer

Lorazepam

Answer

Diazepam

Answer

Chlordiazepoxide

Answer

Alprazolam

Question 3

Naltrexone is contraindicated in a patient who:

Accepted Answer

Is currently taking opioids for pain management

Answer

Has a history of alcohol use disorder

Answer

Has mild renal impairment

Answer

Is enrolled in a smoking cessation program

Question 4

A patient taking disulfiram consumes a small amount of alcohol in a mouthwash. Which reaction is most likely?

Accepted Answer

Mild flushing and tachycardia

Answer

No reaction due to the small amount

Answer

Severe hypotension and respiratory depression

Answer

Seizures and coma

Question 5

Buprenorphine's 'ceiling effect' on respiratory depression is primarily due to its action as a:

Accepted Answer

Partial agonist at mu receptors

Answer

Full opioid agonist at mu receptors

Answer

Full antagonist at kappa receptors

Answer

Pure antagonist at all opioid receptors

Question 6

Which medication used in opioid use disorder treatment also has FDA approval for alcohol use disorder?

Accepted Answer

Naltrexone

Answer

Methadone

Answer

Buprenorphine

Answer

Clonidine

Question 7

A nurse is educating a patient about acamprosate for alcohol use disorder. Which statement is most accurate?

Accepted Answer

Acamprosate helps reduce cravings by modulating glutamate activity

Answer

Acamprosate works best when started before the patient stops drinking

Answer

Acamprosate causes a severe reaction if alcohol is consumed

Answer

Acamprosate is metabolized extensively by the liver