CARN - Certified Addictions Registered Nurse Pharmacology of Addictive Substances Questions and Answers

Question 1

A client with alcohol use disorder is prescribed acamprosate. The nurse should explain that the primary mechanism of action for this medication is to:

Accepted Answer

Restore the balance between GABA and glutamate neurotransmission.

Answer

Create an unpleasant reaction if alcohol is consumed.

Answer

Block the euphoric effects of alcohol by binding to opioid receptors.

Answer

Substitute for alcohol by providing a similar sedating effect.

Question 2

A nurse is caring for a patient experiencing withdrawal from a short-acting opioid like heroin. Which of the following symptoms would the nurse expect to see peak within 1 to 3 days after the last use?

Accepted Answer

Rhinorrhea, muscle aches, and gastrointestinal distress

Answer

Constipation and urinary retention

Answer

Euphoria and sense of calm

Answer

Respiratory depression and constricted pupils

Question 3

A patient is being initiated on naltrexone for the treatment of opioid use disorder. Which statement by the patient indicates a need for further education?

Accepted Answer

"This medication is a partial opioid agonist that will prevent withdrawal."

Answer

"This medication will help reduce my cravings for opioids."

Answer

"I must stop using all opioids for 7-10 days before I start this pill."

Answer

"If I use opioids while taking this, I won't feel the euphoric effects."

Question 4

A nurse is providing education to a client who has been prescribed disulfiram. The nurse should warn the client to avoid which of the following products?

Accepted Answer

Mouthwash containing alcohol

Answer

Foods high in tyramine, such as aged cheeses

Answer

Grapefruit juice

Answer

Nicotine replacement therapy

Question 5

A patient who has been on long-term, high-dose benzodiazepine therapy abruptly stops taking the medication. The nurse should be most concerned about the patient developing:

Accepted Answer

Grand mal seizures

Answer

Hypertensive crisis

Answer

Serotonin syndrome

Answer

Neuroleptic malignant syndrome

Question 6

When comparing the pharmacology of nicotine delivery via electronic cigarettes (vaping) versus traditional combustible cigarettes, which of the following is most accurate?

Accepted Answer

Traditional cigarettes deliver carbon monoxide, while e-cigarettes do not.

Answer

Vaping delivers nicotine to the brain more rapidly than smoking.

Answer

Both methods deliver identical amounts of nicotine per puff.

Answer

E-cigarettes are a non-addictive alternative to smoking.