Cardiac Subspecialty Flashcards
7 cards from real CSC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Cardiac Subspecialty flashcards as text
A patient with pulmonary arterial hypertension (PAH, Group 1) has WHO functional class III symptoms. Vasoreactivity testing with inhaled nitric oxide shows mean PAP decrease to 32 mmHg with cardiac output increase. What does this indicate?
Answer: Positive vasoreactivity test; candidate for long-term calcium channel blocker therapy
A positive vasoreactivity test (mPAP decrease ≥10 mmHg to <40 mmHg with increased or unchanged cardiac output) identifies patients likely to benefit from high-dose CCBs.
A 55-year-old man undergoes pharmacologic nuclear stress testing with regadenoson. Which adverse effect specific to regadenoson should be monitored for in patients with reactive airway disease?
Answer: Bronchospasm due to adenosine receptor activation
Regadenoson activates A2A adenosine receptors but can also stimulate A2B receptors in bronchial smooth muscle, potentially causing bronchospasm in susceptible patients.
A 67-year-old presents with severe mitral regurgitation (ERO 0.45 cm², regurgitant volume 65 mL) due to a flail posterior leaflet. He is asymptomatic with LVEF 58% and LV end-systolic dimension 39 mm. What is the most appropriate management?
Answer: Mitral valve surgery, preferably repair, given severe MR with flail leaflet
Severe primary MR with a flail leaflet, even in asymptomatic patients, carries a high risk of LV dysfunction and warrants referral to a mitral valve repair center.
Which statement best describes the mechanism of action of sacubitril/valsartan (Entresto) in heart failure with reduced ejection fraction?
Answer: Neprilysin inhibition preventing BNP/ANP breakdown combined with AT1 receptor blockade
Sacubitril inhibits neprilysin (preventing natriuretic peptide degradation) while valsartan blocks AT1 receptors, reducing preload, afterload, and fibrosis.
A 62-year-old woman with no cardiac history presents with acute anterior ST elevation MI. Primary PCI is performed at 90 minutes after first medical contact. Post-PCI TIMI flow is 3, but echocardiography shows apical ballooning with hyperkinetic basal segments. What is the most likely diagnosis?
Answer: Takotsubo (stress) cardiomyopathy mimicking STEMI
Apical ballooning with basal hyperkinesis (reverse pattern) in the distribution of multiple coronary territories, despite patent arteries, is the hallmark of Takotsubo cardiomyopathy.
In which clinical scenario is intravascular ultrasound (IVUS) guidance during PCI most strongly supported by evidence to improve outcomes?
Answer: Left main coronary artery PCI and complex bifurcation lesions
IVUS guidance during left main PCI improves stent sizing, deployment, and reduces major adverse cardiac events compared to angiography alone.
A patient with known Wolff-Parkinson-White (WPW) syndrome develops rapid atrial fibrillation with a ventricular rate of 220 bpm and wide, irregular QRS complexes. Which medication is CONTRAINDICATED?
Answer: Adenosine or calcium channel blocker IV
AV nodal blocking agents (adenosine, CCBs, digoxin, beta-blockers) are contraindicated in WPW with AF as they accelerate conduction down the accessory pathway, potentially causing VF.