A patient received IV morphine 4mg in PACU and now has a respiratory rate of 8 breaths/min with pinpoint pupils. The nurse administers naloxone 0.4mg IV. Which outcome requires repeat naloxone dosing?
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A
Respiratory rate increases to 14 breaths/min but patient remains sleepy
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B
Patient becomes agitated and requests pain medication
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C
Respiratory rate of 8 persists after 2-3 minutes
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D
SpO2 increases from 88% to 94% on room air