CAOP Drug Information and Literature Evaluation

Question 1

Which type of drug information resource is considered a tertiary source?

Accepted Answer

Textbook such as Pharmacotherapy: A Pathophysiologic Approach

Answer

Clinical Pharmacology database

Answer

Package insert

Answer

A randomized controlled trial

Question 2

When evaluating a drug information request, which step should be performed FIRST?

Accepted Answer

Clarify background information from the requestor

Answer

Search the literature

Answer

Formulate a response

Answer

Classify the question type

Question 3

A pharmacist reviews a study reporting an odds ratio of 1.0 for a drug-induced event. How should this be interpreted?

Accepted Answer

There is no association between the drug and the event

Answer

The drug doubles the risk of the event

Answer

The drug halves the risk of the event

Answer

The study was not powered adequately

Question 4

Which study design provides the highest level of evidence for evaluating drug efficacy?

Accepted Answer

Randomized controlled trial

Answer

Case-control study

Answer

Cross-sectional study

Answer

Case series

Question 5

What does a 95% confidence interval that crosses 1.0 for a relative risk indicate?

Accepted Answer

The result is not statistically significant

Answer

The result is statistically significant

Answer

The drug is harmful

Answer

The sample size was too large

Question 6

Which PubMed filter is most useful for a pharmacist seeking the best available evidence on a clinical question?

Accepted Answer

Clinical Queries — Therapy

Answer

Case Reports

Answer

Letters to the Editor

Answer

Editorials