Sterile Products and Aseptic Technique Flashcards
6 cards from real CAOP practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Sterile Products and Aseptic Technique flashcards as text
Which type of biological safety cabinet (BSC) is used when preparing hazardous drugs?
Answer: Class II Type B2 BSC
A Class II Type B2 BSC is total-exhaust and externally vented, providing both product and personnel protection required for hazardous drug compounding.
What is the significance of endotoxin testing (LAL test) for parenteral products?
Answer: It detects bacterial endotoxins (pyrogens) that can cause fever and septic shock
The Limulus Amebocyte Lysate (LAL) test detects gram-negative bacterial endotoxins that can cause pyrogenic reactions even if the product is sterile.
Which hand hygiene step is CRITICAL before gowning for sterile compounding?
Answer: Performing a surgical hand scrub with an antimicrobial agent for at least 30 seconds
A thorough antiseptic hand scrub removes transient microorganisms and reduces resident flora before donning sterile gloves for aseptic compounding.
A pharmacist notices visible particles in a prepared IV bag. The CORRECT action is to:
Answer: Quarantine and discard the preparation, then investigate the cause
Visible particulate matter indicates contamination or incompatibility; the preparation must be discarded and the root cause investigated to prevent patient harm.
What is the function of a 0.22-micron filter used in IV admixture preparation?
Answer: Sterilizes the solution by removing bacteria and particulates ≥0.22 µm
A 0.22-micron sterilizing filter removes bacteria, fungi, and particulate matter, providing terminal sterilization for preparations that cannot be autoclaved.
According to USP , which condition requires Category 2 BUD assignment for a compounded sterile preparation?
Answer: Prepared from non-sterile components or requiring extended storage
Category 2 CSPs involve more complex conditions, including use of non-sterile starting materials or extended storage, requiring more rigorous sterility testing and shorter BUDs.