Drug Information and Literature Evaluation Flashcards
6 cards from real CAOP practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Drug Information and Literature Evaluation flashcards as text
Which type of drug information resource is considered a tertiary source?
Answer: Textbook such as Pharmacotherapy: A Pathophysiologic Approach
Tertiary sources are comprehensive compiled references such as textbooks that synthesize information from primary and secondary sources.
When evaluating a drug information request, which step should be performed FIRST?
Answer: Clarify background information from the requestor
Obtaining background information about the patient and the specific context of the question is the essential first step before any literature search.
A pharmacist reviews a study reporting an odds ratio of 1.0 for a drug-induced event. How should this be interpreted?
Answer: There is no association between the drug and the event
An odds ratio of 1.0 indicates no difference in odds between exposed and unexposed groups, meaning no association exists.
Which study design provides the highest level of evidence for evaluating drug efficacy?
Answer: Randomized controlled trial
Randomized controlled trials are at the top of the evidence hierarchy for evaluating causality and drug efficacy due to their controlled, unbiased design.
What does a 95% confidence interval that crosses 1.0 for a relative risk indicate?
Answer: The result is not statistically significant
A confidence interval crossing 1.0 for a relative risk means the null hypothesis (no effect) cannot be excluded, indicating a non-significant result.
Which PubMed filter is most useful for a pharmacist seeking the best available evidence on a clinical question?
Answer: Clinical Queries — Therapy
PubMed's Clinical Queries filter with the Therapy category uses validated search strategies designed to retrieve high-quality evidence for treatment questions.