Canadian Entry To Practice Canadian Entry To Practice Sterile Products 3

Question 1

What does the term 'first air' refer to in aseptic technique?

Accepted Answer

Uninterrupted HEPA-filtered air directly from the filter face

Answer

First air is the HEPA-filtered air flowing directly from the filter uninterrupted by any object, and critical sites must always be exposed to first air.

Question 2

When preparing a chemotherapy agent, which personal protective equipment (PPE) is specifically required beyond standard garbing?

Accepted Answer

Double chemotherapy-tested gloves and a closed-front gown

Answer

Preparation of hazardous chemotherapy requires double chemotherapy-tested gloves and a closed-front, cuffed, low-permeability gown to prevent skin absorption.

Question 3

A pharmacy technician notices that a laminar airflow workbench alarm is sounding and airflow is compromised. What is the correct action?

Accepted Answer

Stop compounding and quarantine all preparations made during the malfunction

Answer

All preparations made during a compromised airflow event must be quarantined and investigated before any release, as sterility cannot be assured.

Question 4

Which parameter is most important to verify when preparing a large-volume parenteral (LVP) admixture?

Accepted Answer

Final drug concentration, volume, and compatibility

Answer

Verifying final concentration, total volume, and drug-drug/drug-solution compatibility ensures the LVP admixture is safe and effective for the patient.

Question 5

What is the recommended alcohol concentration for disinfecting surfaces and critical sites in sterile compounding?

Accepted Answer

70% isopropyl alcohol

Answer

70% isopropyl alcohol is most effective for surface disinfection because it denatures proteins while maintaining sufficient moisture contact time to kill microorganisms.