CAC Pharmacology and Substance Knowledge

Question 1

Which FDA-approved medication for alcohol use disorder works by causing an unpleasant reaction when alcohol is consumed?

Accepted Answer

Disulfiram (Antabuse)

Answer

Naltrexone (Vivitrol)

Answer

Acamprosate (Campral)

Answer

Buprenorphine (Suboxone)

Question 2

Methadone maintenance treatment for opioid use disorder is dispensed through:

Accepted Answer

SAMHSA-certified Opioid Treatment Programs (OTPs)

Answer

Any licensed pharmacy with a prescription

Answer

Emergency departments only

Answer

Primary care physician offices

Question 3

Which class of substances produces withdrawal symptoms that can be life-threatening without medical management?

Accepted Answer

Alcohol and benzodiazepines

Answer

Opioids and stimulants

Answer

Cannabis and hallucinogens

Answer

Opioids and cannabis

Question 4

Buprenorphine (Suboxone) is a partial opioid agonist. What is the clinical significance of the 'ceiling effect'?

Accepted Answer

At higher doses, the euphoric and respiratory depression effects plateau, reducing overdose risk

Answer

The medication stops working after a maximum dose is reached

Answer

Clients cannot become physically dependent on buprenorphine

Answer

Higher doses cause increasingly severe sedation

Question 5

Which neurotransmitter is MOST centrally involved in the reward pathway dysregulation that underlies addiction?

Accepted Answer

Dopamine

Answer

Serotonin

Answer

Norepinephrine

Answer

GABA

Question 6

Which medication is used to reverse opioid overdose and should be available in addiction treatment settings?

Accepted Answer

Naloxone (Narcan)

Answer

Naltrexone (Vivitrol)

Answer

Flumazenil (Romazicon)

Answer

Acamprosate (Campral)