BRPT Sleep Physiology and Neuroanatomy 3

Question 1

The glymphatic system, active primarily during sleep, functions to:

Accepted Answer

Clear adenosine and metabolic waste from brain tissue

Answer

Generate slow-wave EEG activity

Answer

Regulate melatonin release

Answer

Transmit circadian signals to peripheral organs

Question 2

Which term describes the recurring 90–110 minute NREM-REM cycling pattern that repeats throughout the night?

Accepted Answer

Ultradian rhythm

Answer

Circadian rhythm

Answer

REM rebound

Answer

Homeostatic oscillation

Question 3

During REM sleep, thermoregulation is suppressed and humans temporarily become:

Accepted Answer

Poikilothermic (unable to thermoregulate)

Answer

Hyperthermic

Answer

Hypothermic

Answer

Unaffected by ambient temperature

Question 4

The circadian nadir of core body temperature and peak sleepiness in a normal sleeper typically occurs at approximately:

Accepted Answer

2 AM – 4 AM

Answer

11 PM – 1 AM

Answer

6 AM – 8 AM

Answer

12 PM – 2 PM

Question 5

The ventrolateral preoptic area (VLPO) promotes sleep onset by:

Accepted Answer

Releasing GABA and galanin to inhibit wake-promoting nuclei

Answer

Activating orexin neurons in the lateral hypothalamus

Answer

Stimulating the ascending reticular activating system

Answer

Increasing cortisol secretion

Question 6

Normal REM latency (time from sleep onset to first REM period) in healthy adults is approximately:

Accepted Answer

70–100 minutes

Answer

20–30 minutes

Answer

45–60 minutes

Answer

120–150 minutes