Board Certified Ophthalmologist Uveitis and Ocular Inflammation 3

Question 1

Which HLA type is most strongly associated with birdshot chorioretinopathy?

Accepted Answer

HLA-A29

Answer

HLA-B27

Answer

HLA-B51

Answer

HLA-DR15

Question 2

A patient presents with recurrent episodes of markedly elevated intraocular pressure (40–60 mmHg) with minimal anterior chamber cells or flare, and unilateral corneal edema. What is the most likely diagnosis?

Accepted Answer

Posner-Schlossman syndrome (glaucomatocyclitic crisis)

Answer

Ankylosing spondylitis–associated uveitis

Answer

Behçet disease

Answer

Fuchs heterochromic iridocyclitis

Question 3

What is the standard treatment regimen for active toxoplasmic retinochoroiditis threatening the macula?

Accepted Answer

Pyrimethamine + sulfadiazine + folinic acid (with adjunct corticosteroids)

Answer

Acyclovir plus systemic corticosteroids

Answer

Oral valganciclovir monotherapy

Answer

Intravitreal triamcinolone acetonide alone

Question 4

Which imaging modality is most sensitive for detecting subclinical choroidal involvement in Vogt-Koyanagi-Harada syndrome?

Accepted Answer

Indocyanine green angiography (ICGA)

Answer

Fundus fluorescein angiography (FFA)

Answer

Spectral-domain OCT

Answer

B-scan ultrasonography

Question 5

Which subtype of juvenile idiopathic arthritis (JIA) carries the highest risk of developing chronic anterior uveitis?

Accepted Answer

Oligoarticular JIA in ANA-positive young girls

Answer

Systemic JIA (Still's disease)

Answer

Polyarticular RF-positive JIA

Answer

Enthesitis-related JIA

Question 6

In a patient with JIA-associated uveitis refractory to topical steroids and methotrexate, which biologic agent has FDA approval for this indication?

Accepted Answer

Adalimumab

Answer

Infliximab

Answer

Rituximab

Answer

Tocilizumab

Question 7

Which finding on FFA is most characteristic of active Vogt-Koyanagi-Harada syndrome during the acute uveitic phase?

Accepted Answer

Multiple focal areas of subretinal fluid with pinpoint hyperfluorescent leaks at the RPE level

Answer

Retinal arterial occlusions with ischemic whitening

Answer

Extensive chorioretinal atrophy with window defects

Answer

Disc leakage only with no choroidal involvement