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Uveitis and Ocular Inflammation Flashcards

7 cards from real Board Certified Ophthalmologist practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A 25-year-old male presents with acute anterior uveitis and lower back pain. HLA-B27 testing is positive. Which condition is most likely associated with this presentation?

    Answer: Ankylosing spondylitis

    HLA-B27-positive acute anterior uveitis with sacroiliitis or lower back pain is classically associated with ankylosing spondylitis, a seronegative spondyloarthropathy.

  2. What is the classic appearance of keratic precipitates (KPs) in granulomatous uveitis?

    Answer: Large, greasy 'mutton-fat' KPs in the inferior cornea

    Granulomatous uveitis is characterized by large, greasy 'mutton-fat' KPs that accumulate in the inferior cornea due to aqueous convection currents.

  3. A patient with intermediate uveitis shows 'snowballs' in the vitreous and 'snowbanking' over the pars plana. Which condition is most likely?

    Answer: Pars planitis

    Pars planitis is a form of idiopathic intermediate uveitis characterized by vitreous snowballs and snowbank (exudate) formation overlying the pars plana.

  4. Which class of medication is the first-line treatment for non-infectious uveitis?

    Answer: Corticosteroids

    Corticosteroids—topical, periocular, or systemic—are the first-line agents for non-infectious uveitis due to their potent and rapid anti-inflammatory effect.

  5. A patient presents with bilateral granulomatous panuveitis, sunset glow fundus, vitiligo, poliosis, and alopecia. What is the most likely diagnosis?

    Answer: Vogt-Koyanagi-Harada syndrome

    VKH syndrome is characterized by bilateral granulomatous uveitis, sunset glow fundus from choroidal depigmentation, and extraocular findings including vitiligo, poliosis, and alopecia.

  6. Weeks after penetrating trauma to the right eye, a patient develops inflammation in the uninjured left eye. What is the diagnosis?

    Answer: Sympathetic ophthalmia

    Sympathetic ophthalmia is a bilateral granulomatous panuveitis arising after penetrating trauma or surgery to one eye (the exciting eye), affecting the fellow sympathizing eye via autoimmune sensitization to uveal antigens.

  7. A patient presents with recurrent hypopyon uveitis, painful oral ulcers, and genital ulcers. What is the most likely diagnosis?

    Answer: Behçet disease

    Behçet disease classically presents with the triad of recurrent oral ulcers, genital ulcers, and uveitis (often with hypopyon), and is more severe in patients of Middle Eastern or Asian descent.