Retina and Vitreous Disorders Flashcards
7 cards from real Board Certified Ophthalmologist practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Retina and Vitreous Disorders flashcards as text
A 'dark choroid' on fluorescein angiography in a teenager with central vision loss and yellow pisciform flecks suggests which gene defect?
Answer: ABCA4
Stargardt disease comes from ABCA4 mutations; lipofuscin in the RPE blocks choroidal fluorescence and causes the dark choroid.
A patient has retinitis pigmentosa and congenital sensorineural hearing loss. What is the most likely diagnosis?
Answer: Usher syndrome
Usher syndrome is the most common syndromic cause of RP and has sensorineural hearing loss.
Scalloped areas of chorioretinal atrophy in the mid-periphery, together with hyperornithinemia, respond to which dietary treatment?
Answer: Arginine-restricted diet with pyridoxine
Gyrate atrophy (OAT deficiency) is managed with an arginine-restricted diet, and some patients respond to vitamin B6.
Which treatment has the best evidence for chronic central serous chorioretinopathy with persistent subretinal fluid?
Answer: Half-dose verteporfin photodynamic therapy
Half-dose (or half-fluence) PDT gave better subretinal fluid resolution than micropulse laser in the PLACE trial, and it is preferred for chronic CSC.
Which hemoglobinopathy is most often associated with proliferative sickle retinopathy?
Answer: HbSC
HbSC disease has the highest rate of proliferative 'sea fan' retinopathy, even though it causes milder systemic disease than HbSS.
Under ETROP criteria, which retinopathy of prematurity finding is Type 1 ROP needing treatment?
Answer: Zone II, stage 2, with plus disease
Type 1 ROP includes zone II stage 2 or 3 with plus, zone I any stage with plus, and zone I stage 3 without plus.
A 7-year-old boy has unilateral retinal telangiectasias with extensive yellow intraretinal and subretinal exudation. What is the most likely diagnosis?
Answer: Coats disease
Coats disease typically appears in young males as a unilateral condition with telangiectatic vessels and heavy lipid exudation.