FREE Retina and Vitreous Disorders Questions and Answers Flashcards
6 cards from real Board Certified Ophthalmologist practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 FREE Retina and Vitreous Disorders Questions and Answers flashcards as text
Which gene mutation is most commonly associated with Best vitelliform macular dystrophy?
Answer: BEST1 (VMD2)
Best vitelliform macular dystrophy is caused by mutations in the BEST1 gene (formerly VMD2), which encodes bestrophin-1, a chloride channel in the retinal pigment epithelium.
A 30-year-old man presents with floaters and blurred vision. Examination reveals snowbanking of the inferior pars plana and vitritis. What is the most likely diagnosis?
Answer: Intermediate uveitis (pars planitis)
Snowbanking over the inferior pars plana with vitritis is the hallmark finding of intermediate uveitis, also known as pars planitis.
What is the recommended initial treatment for zone 1 retinopathy of prematurity (ROP) with plus disease?
Answer: Intravitreal anti-VEGF injection
Intravitreal anti-VEGF injection has become the preferred first-line treatment for zone 1 ROP with plus disease due to superior structural outcomes compared to laser in this posterior location.
A patient with sickle cell disease develops proliferative retinopathy. In which retinal location do sea-fan neovascular lesions most commonly arise?
Answer: Peripheral retina at the border of perfused and non-perfused zones
Sea-fan neovascularization in sickle cell retinopathy characteristically develops at the junction between perfused and non-perfused peripheral retina.
Which of the following is the most accurate method for measuring macular hole diameter to guide surgical prognosis?
Answer: Spectral-domain OCT measurement of the minimum linear diameter
Spectral-domain OCT provides precise measurement of the minimum linear diameter of a macular hole, which is the strongest predictor of anatomic closure after vitrectomy.
A 55-year-old patient presents with metamorphopsia and a grayish-green subretinal lesion temporal to the fovea. Fundus autofluorescence shows a hyperautofluorescent halo around the lesion. What is the most likely diagnosis?
Answer: Choroidal neovascular membrane secondary to AMD
A grayish-green subretinal lesion with a hyperautofluorescent halo on fundus autofluorescence in a patient with metamorphopsia is characteristic of a choroidal neovascular membrane in the setting of AMD.