FREE Board Certified Ophthalmologist Cornea and External Disease Questions and Answers Flashcards
6 cards from real Board Certified Ophthalmologist practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 FREE Board Certified Ophthalmologist Cornea and External Disease Questions and Answers flashcards as text
A patient develops a shield ulcer in the superior cornea associated with giant papillae on the upper tarsal conjunctiva. What is the underlying diagnosis?
Answer: Vernal or atopic keratoconjunctivitis
Shield ulcers are a complication of severe vernal or atopic keratoconjunctivitis caused by mechanical trauma from giant papillae and inflammatory mediators.
What is the recommended first-line treatment for herpes simplex virus epithelial (dendritic) keratitis?
Answer: Topical ganciclovir or oral valacyclovir
HSV epithelial keratitis is treated with topical antivirals (ganciclovir gel) or oral antivirals (valacyclovir/acyclovir) to reduce viral replication.
In a patient with Mooren ulcer, what is the characteristic pattern of corneal involvement?
Answer: Peripheral ulcerative keratitis with undermined leading edge progressing centrally
Mooren ulcer is an autoimmune peripheral ulcerative keratitis with a characteristic undermined, overhanging central edge that progresses circumferentially and centrally.
Which corneal dystrophy is associated with mutations in the TGFBI gene on chromosome 5q31 and presents with granular opacities in the anterior stroma?
Answer: Granular corneal dystrophy type I (classic)
Granular dystrophy type I is caused by TGFBI mutations and features discrete, crumb-like hyaline deposits in the anterior central stroma with clear intervening spaces.
A corneal transplant patient develops an epithelial rejection line (Khodadoust line) 8 months postoperatively. What is the appropriate initial management?
Answer: Intensive topical corticosteroids (prednisolone acetate 1% every hour)
Endothelial graft rejection presenting with a Khodadoust line requires aggressive topical corticosteroids initiated immediately to prevent irreversible endothelial cell loss.
What is the most common organism causing bacterial keratitis in contact lens wearers in the United States?
Answer: Pseudomonas aeruginosa
Pseudomonas aeruginosa is the most common cause of contact lens-related bacterial keratitis, producing a rapidly progressive suppurative ulcer.