Board Certified Ophthalmologist Retina and Vitreous Diseases Questions and Answers Flashcards
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A 55-year-old diabetic patient has hard exudates arranged in a circinate pattern temporal to the fovea with macular thickening on OCT. What is the first-line treatment?
Answer: Intravitreal anti-VEGF injection
Intravitreal anti-VEGF therapy is now first-line for center-involving diabetic macular edema, as demonstrated by the DRCR.net Protocol T trial.
Which type of retinal detachment is most commonly associated with intraocular tumors such as choroidal melanoma?
Answer: Exudative retinal detachment
Intraocular tumors cause exudative (serous) retinal detachment by disrupting the blood-retinal barrier and producing subretinal fluid without a retinal break.
What is the characteristic OCT finding in central serous chorioretinopathy?
Answer: Neurosensory retinal detachment with subretinal fluid
Central serous chorioretinopathy classically shows a dome-shaped neurosensory retinal detachment with optically clear subretinal fluid on OCT.
In retinopathy of prematurity, at which zone does disease carry the worst visual prognosis?
Answer: Zone I
Zone I disease in ROP carries the worst prognosis because it involves the most posterior retina closest to the optic nerve and macula.
A patient presents with bilateral vitritis, retinal vasculitis, and candle-wax drippings along retinal venules. What is the most likely systemic diagnosis?
Answer: Sarcoidosis
Candle-wax drippings (taches de bougie) along retinal venules are a hallmark of ocular sarcoidosis with granulomatous periphlebitis.
Which vitamin supplementation regimen was shown by the AREDS2 study to reduce progression of intermediate to advanced age-related macular degeneration?
Answer: Vitamin C, vitamin E, lutein, zeaxanthin, and zinc
The AREDS2 formula replaced beta-carotene with lutein and zeaxanthin, combined with vitamins C, E, and zinc, to safely reduce AMD progression risk.