BHS Pharmacology and Therapeutics

Question 1

What term describes the time required for the plasma concentration of a drug to decrease by 50%?

Accepted Answer

Half-life

Answer

Bioavailability

Answer

Clearance rate

Answer

Volume of distribution

Question 2

Which route of drug administration provides 100% bioavailability?

Accepted Answer

Intravenous (IV)

Answer

Oral

Answer

Subcutaneous

Answer

Transdermal

Question 3

What is the 'therapeutic index' of a drug?

Accepted Answer

The ratio between the toxic dose and the effective dose

Answer

The time to peak drug effect

Answer

The percentage of the drug absorbed by the body

Answer

The speed at which a drug is metabolized

Question 4

Which liver enzyme system is primarily responsible for the metabolism of most drugs in humans?

Accepted Answer

Cytochrome P450 (CYP450)

Answer

Monoamine oxidase (MAO)

Answer

Acetylcholinesterase

Answer

Alcohol dehydrogenase

Question 5

A patient taking a beta-blocker for hypertension develops bradycardia. This is an example of which type of drug effect?

Accepted Answer

Adverse drug reaction (side effect)

Answer

Allergic reaction

Answer

Drug-drug interaction

Answer

Idiosyncratic reaction

Question 6

Which class of antibiotics works by inhibiting bacterial cell wall synthesis?

Accepted Answer

Penicillins and cephalosporins

Answer

Fluoroquinolones

Answer

Macrolides

Answer

Tetracyclines