BE/B Eng Bachelor of Engineering Bachelor of Biomedical Engineering 5

Question 1

Which principle governs the diffusion of oxygen from alveoli into pulmonary capillaries?

Accepted Answer

Fick's law of diffusion

Answer

Fick's law states that the net diffusion rate of a gas across a membrane is proportional to the surface area, the concentration (partial pressure) gradient, and the membrane's diffusion coefficient, and inversely proportional to membrane thickness.

Question 2

When designing a bioreactor for tissue engineering, which environmental parameter is NOT typically monitored and controlled?

Accepted Answer

Gravitational field strength

Answer

Bioreactor design focuses on controlling biochemical parameters (pH, O₂, CO₂) and mechanical stimuli (perfusion, compression, rotation), but gravitational field strength is a fixed environmental constant that is not actively controlled in standard lab bioreactors.

Question 3

In the context of ISO 10993, biocompatibility testing of a medical device evaluates the material's potential to cause:

Accepted Answer

Adverse biological responses including cytotoxicity, sensitization, and genotoxicity

Answer

ISO 10993 is a series of standards that defines biological evaluation tests—such as cytotoxicity, sensitization, irritation, systemic toxicity, and genotoxicity—to assess if a medical device or its materials could harm patients.

Question 4

In biomedical optics, the 'therapeutic window' refers to the range of wavelengths that:

Accepted Answer

Penetrate tissue most deeply due to minimal absorption by water, hemoglobin, and melanin

Answer

The near-infrared therapeutic window (~650–1350 nm) is the spectral region where tissue scattering and absorption by major chromophores (water, oxy/deoxyhemoglobin, melanin) are minimized, allowing the deepest light penetration.

Question 5

A biomedical engineer is reviewing a receiver operating characteristic (ROC) curve for a diagnostic test. What does the area under the curve (AUC) represent?

Accepted Answer

The overall ability of the test to discriminate between diseased and non-diseased populations

Answer

The AUC of a ROC curve is a single scalar value summarizing the test's discriminative ability across all possible thresholds; an AUC of 1.0 is perfect discrimination, while 0.5 represents chance-level performance.

BE/B Eng Bachelor of Engineering Practice Test

BE/B Eng Bachelor of Engineering Practice Test

BE/B Eng Bachelor of Engineering Bachelor of Biomedical Engineering 5