Insulin Therapy Flashcards
7 cards from real BC ADM practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Insulin Therapy flashcards as text
Which statement about insulin storage is most accurate for clinical practice?
Answer: Unopened insulin should be refrigerated; in-use insulin can be kept at room temperature up to 28–30 days
Unopened insulin should be refrigerated (36–46°F); once opened, most formulations remain stable at room temperature (up to ~77°F) for 28–30 days depending on the product.
A patient with type 2 diabetes on premixed insulin 70/30 twice daily has good fasting glucose but high post-lunch values. The most physiologically rational adjustment is:
Answer: Add a rapid-acting insulin dose before lunch
Premixed 70/30 provides coverage mainly for breakfast and dinner; adding a separate rapid-acting dose at lunch directly addresses the uncontrolled midday postprandial rise.
The pharmacologic rationale for combining insulin degludec with liraglutide (IDegLira) includes:
Answer: GLP-1 agonist activity mitigates insulin-associated weight gain and reduces hypoglycemia risk
GLP-1 receptor agonists promote satiety and weight loss while stimulating glucose-dependent insulin secretion, counteracting insulin-associated weight gain and reducing hypoglycemia risk.
Insulin resistance in a hospitalized patient is MOST likely to increase insulin requirements due to:
Answer: Counter-regulatory hormone surges during physiologic stress
Physiologic stress triggers release of epinephrine, cortisol, glucagon, and growth hormone, causing marked insulin resistance and increased glucose production.
A patient using an insulin pen forgets to prime (perform an air shot) before injection. The most likely consequence is:
Answer: Delivery of an inaccurate (smaller) insulin dose
Failure to prime the pen needle can result in air displacement within the pen mechanism, leading to delivery of less insulin than dialed.
Which insulin regimen most closely mimics physiologic insulin secretion in type 1 diabetes?
Answer: Basal-bolus regimen with long-acting basal plus rapid-acting insulin at each meal
Basal-bolus therapy with a long-acting insulin providing background coverage plus rapid-acting analogs at mealtimes best replicates normal pancreatic insulin secretion patterns.
When rotating insulin injection sites, the clinician should advise that absorption is fastest from which anatomic location?
Answer: Abdomen (periumbilical region excluded)
Subcutaneous abdominal tissue has the most vascular supply and least connective tissue of common injection sites, making insulin absorption fastest there.