Bachelor of Pharmacy (B.Pharm.) Pharmaceutics Flashcards
7 cards from real B.Pharm. Bachelor of Pharmacy practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
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In tablet manufacturing, the process of compressing granules into a tablet is called:
Answer: Compression
Compression is the final step where granules are fed into a die and punched under high pressure to form tablets.
Which excipient functions as a disintegrant in tablet formulations?
Answer: Sodium starch glycolate
Sodium starch glycolate is a superdisintegrant that rapidly absorbs water and swells, breaking the tablet apart.
The Noyes-Whitney equation describes the rate of drug dissolution as dependent on:
Answer: Surface area and concentration gradient
The Noyes-Whitney equation: dM/dt = DA(Cs−C)/h, where surface area and concentration gradient are key variables.
Enteric coating on tablets is designed to dissolve at a pH above:
Answer: 5.5
Enteric polymers like cellulose acetate phthalate dissolve above pH 5.5–6.0, allowing intact passage through the acidic stomach.
Which parameter best describes the spread of residence times of molecules passing through a flow-through system in pharmacokinetics?
Answer: Mean residence time (MRT)
MRT represents the average time a drug molecule resides in the body and accounts for all disposition processes.
A drug formulated as a controlled-release pellet system is often coated with ethylcellulose because it:
Answer: Forms a water-insoluble membrane controlling diffusion
Ethylcellulose is a water-insoluble polymer that forms a rate-controlling membrane allowing slow diffusion of drug.
Isotonicity adjustment of ophthalmic solutions is critical because solutions that are hypotonic can cause:
Answer: Swelling and rupture of corneal cells
Hypotonic solutions have lower osmolarity than tears, causing water to flow into corneal cells by osmosis, leading to swelling.