Pharmacology Flashcards
7 cards from real ATC practice questions. Tap to flip, then mark Knew It or Still Learning โ missed cards come back until you master them.
Read the first 7 Pharmacology flashcards as text
A collegiate athlete tests positive for a banned substance after using a contaminated dietary supplement. Under WADA rules, which principle governs this outcome?
Answer: Strict liability
WADA's strict liability principle holds athletes responsible for any prohibited substance found in their body regardless of intent or source.
Which NSAID is generally considered safest for athletes with mild renal impairment when short-term use is necessary?
Answer: Celecoxib
Celecoxib (a COX-2 selective inhibitor) has less impact on renal prostaglandins at standard doses compared to non-selective NSAIDs.
An athletic trainer notices an athlete is using a topical NSAID on a muscle contusion. What is a key advantage of topical over oral NSAID delivery?
Answer: Reduced gastrointestinal side effects
Topical NSAIDs achieve local therapeutic concentrations while significantly reducing systemic absorption and GI adverse effects.
Which controlled substance schedule includes drugs with no currently accepted medical use in the United States?
Answer: Schedule I
Schedule I drugs, such as heroin and LSD, have no accepted medical use and a high potential for abuse under the Controlled Substances Act.
An athlete on a selective serotonin reuptake inhibitor (SSRI) for depression begins a new training block. Which drug-exercise interaction concern should be monitored?
Answer: Increased risk of hyponatremia with prolonged endurance events
SSRIs can impair renal water excretion; combined with excessive fluid intake during prolonged exercise, this may cause exercise-associated hyponatremia.
What is the primary mechanism by which opioid analgesics reduce pain?
Answer: Binding to mu, kappa, and delta receptors in the CNS to inhibit pain signaling
Opioids exert analgesia primarily by binding to opioid receptors (especially mu) in the brain and spinal cord, inhibiting pain signal transmission.
A football player is prescribed methylphenidate for ADHD. Which governing body must be notified for a Therapeutic Use Exemption (TUE) in NCAA-regulated competition?
Answer: The NCAA
NCAA athletes must obtain a TUE through the NCAA or their institution's procedures for banned stimulants used therapeutically.