ASPD ASPD Neurobiological and Genetic Factors

Question 1

Which brain region is most consistently implicated in the reduced emotional processing seen in individuals with ASPD?

Accepted Answer

Amygdala

Answer

Hippocampus

Answer

Cerebellum

Answer

Thalamus

Question 2

Twin studies on antisocial behavior in ASPD suggest that heritability accounts for approximately what percentage of variance?

Accepted Answer

40-60%

Answer

10-20%

Answer

80-90%

Answer

Less than 5%

Question 3

Which neurotransmitter system is most strongly associated with impulsivity and aggression in ASPD?

Accepted Answer

Serotonin

Answer

Dopamine

Answer

GABA

Answer

Acetylcholine

Question 4

What does neuroimaging research consistently show about prefrontal cortex volume in individuals diagnosed with ASPD?

Accepted Answer

Reduced gray matter volume

Answer

Increased gray matter volume

Answer

Normal volume with hyperactivity

Answer

Enlarged white matter tracts

Question 5

The 'callous-unemotional' trait in youth that predicts adult ASPD is most closely linked to dysfunction in which biological system?

Accepted Answer

Mirror neuron and empathy circuits

Answer

Hypothalamic-pituitary-adrenal (HPA) axis

Answer

Digestive microbiome

Answer

Visual cortex pathways

Question 6

Which gene variant has been most studied in relation to aggressive antisocial behavior in ASPD research?

Accepted Answer

MAOA (monoamine oxidase A)

Answer

BRCA1

Answer

ApoE4

Answer

HTT (serotonin transporter)