Practice Test GeeksASCP Practice Test
← All ASCP Flashcard Decks

Clinical Chemistry Flashcards

6 cards from real ASCP practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 6 Clinical Chemistry flashcards as text

  1. Phenylketonuria (PKU) is detected by measuring elevated levels of which metabolite?

    Answer: Phenylalanine

    PKU results from phenylalanine hydroxylase deficiency, causing phenylalanine accumulation in blood and urine.

  2. Which tumor marker is most useful for monitoring treatment response in prostate cancer?

    Answer: PSA

    Prostate-specific antigen (PSA) is produced by prostate epithelium and is the primary biomarker for monitoring prostate cancer.

  3. The reference method for cholesterol measurement uses which technique?

    Answer: Abell-Kendall method with Liebermann-Burchard reagent

    The Abell-Kendall method is the CDC reference method for total cholesterol, used to calibrate all clinical enzymatic assays.

  4. Which enzyme deficiency causes phenylketonuria?

    Answer: Phenylalanine hydroxylase

    Phenylalanine hydroxylase converts phenylalanine to tyrosine; its deficiency causes toxic phenylalanine accumulation.

  5. A serum sodium of 118 mEq/L is classified as:

    Answer: Severe hyponatremia

    Severe hyponatremia is defined as serum sodium below 120–125 mEq/L and requires urgent treatment to prevent cerebral edema.

  6. Which test distinguishes prerenal azotemia from intrinsic renal failure?

    Answer: BUN/creatinine ratio

    A BUN/creatinine ratio >20:1 suggests prerenal azotemia, while a ratio of 10–15:1 is more consistent with intrinsic renal disease.