ASCP Immunohematology (Blood Banking) 2

Question 1

Cryoprecipitate is the treatment of choice for which specific clotting factor deficiency?

Accepted Answer

Hemophilia A (Factor VIII deficiency)

Answer

Factor X deficiency

Answer

Factor V deficiency

Answer

Vitamin K deficiency

Question 2

Which blood group system is associated with the 'Bombay phenotype' (Oh) lacking the H antigen?

Accepted Answer

H system (FUT1 gene)

Answer

ABO system

Answer

Lewis system

Answer

Kell system

Question 3

Transfusion-related acute lung injury (TRALI) is primarily caused by:

Accepted Answer

Donor anti-HLA or anti-neutrophil antibodies reacting with recipient

Answer

ABO incompatibility

Answer

Bacterial contamination of platelets

Answer

Iron overload

Question 4

Which RhIG (RhoGAM) dose is given at 28 weeks gestation for Rh prophylaxis?

Accepted Answer

300 µg (full dose)

Answer

50 µg (minidose)

Answer

150 µg

Answer

600 µg

Question 5

Which test detects unexpected antibodies in a patient's serum before transfusion?

Accepted Answer

Antibody screen (indirect antiglobulin test)

Answer

ABO typing

Answer

Rh typing

Answer

Direct antiglobulin test

Question 6

The Kleihauer-Betke test is used to:

Accepted Answer

Detect fetal-maternal hemorrhage by quantifying fetal cells in maternal blood

Answer

Identify blood group antibodies

Answer

Type HLA antigens

Answer

Screen for hemolytic disease