ASCP Clinical Chemistry 2

Question 1

Which method is the reference standard for measuring serum creatinine?

Accepted Answer

Enzymatic method with isotope dilution mass spectrometry (IDMS)

Answer

Jaffe colorimetric method

Answer

Bradford protein assay

Answer

Biuret method

Question 2

A patient has pH 7.28, PCO2 55 mmHg, and HCO3 24 mEq/L. This is consistent with:

Accepted Answer

Respiratory acidosis

Answer

Metabolic acidosis

Answer

Metabolic alkalosis

Answer

Respiratory alkalosis

Question 3

Which analyte is measured by the Berthelot reaction in clinical chemistry?

Accepted Answer

Ammonia/urea nitrogen (BUN)

Answer

Glucose

Answer

Creatinine

Answer

Bilirubin

Question 4

Which fraction of bilirubin is elevated in hepatocellular disease and obstructive jaundice?

Accepted Answer

Both conjugated and unconjugated

Answer

Unconjugated (indirect) only

Answer

Conjugated (direct) only

Answer

Delta bilirubin only

Question 5

The Friedewald equation calculates LDL cholesterol using which formula?

Accepted Answer

LDL = Total cholesterol − HDL − (TG/5)

Answer

LDL = Total cholesterol − HDL

Answer

LDL = HDL + VLDL

Answer

LDL = Total cholesterol × 0.7

Question 6

Which electrolyte imbalance is most associated with peaked T-waves on ECG?

Accepted Answer

Hyperkalemia

Answer

Hyponatremia

Answer

Hypocalcemia

Answer

Hypomagnesemia