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Stroke Prevention & Risk Management Flashcards

7 cards from real ASC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A 72-year-old woman with non-valvular AF and CKD (eGFR 28 mL/min) requires anticoagulation for stroke prevention. Which DOAC requires the most careful dose adjustment or avoidance in this setting?

    Answer: Dabigatran

    Dabigatran is predominantly renally cleared (~80%) and is contraindicated when eGFR <30 mL/min, making it the highest-risk DOAC in severe CKD.

  2. Which imaging modality is most sensitive for detecting a carotid plaque vulnerable to causing embolic stroke?

    Answer: High-resolution MRI vessel wall imaging

    High-resolution MRI vessel wall imaging can characterize plaque composition, intraplaque hemorrhage, and fibrous cap integrity, identifying vulnerable plaques at greatest embolic risk.

  3. The INTERSTROKE study identified what proportion of global stroke risk attributable to ten modifiable risk factors?

    Answer: Approximately 90%

    The INTERSTROKE study found that ten modifiable risk factors—led by hypertension—account for approximately 90% of population-attributable stroke risk worldwide.

  4. A patient with sickle cell disease and prior overt stroke is on a chronic transfusion program. What is the primary hemoglobin S target to maintain?

    Answer: HbS <30%

    Chronic transfusion programs for sickle cell disease aim to maintain HbS below 30% to reduce the risk of recurrent overt stroke.

  5. A stroke coordinator assesses a patient for smoking cessation as part of secondary prevention. Compared to never-smokers, current smokers have approximately what relative risk of ischemic stroke?

    Answer: 2-fold increased risk

    Current smokers have approximately twice the risk of ischemic stroke compared to non-smokers, and this risk decreases substantially within 2–5 years of cessation.

  6. In a patient with vertebrobasilar TIA attributed to posterior circulation atherosclerosis, the MOST critical imaging study to guide secondary prevention is:

    Answer: CT angiography or MR angiography of the posterior circulation vessels

    CTA or MRA of the posterior circulation (vertebral and basilar arteries) is essential to identify stenosis, dissection, or occlusion guiding antithrombotic and revascularization decisions.

  7. Which statement best describes the role of statin therapy in hemorrhagic stroke patients regarding future prevention?

    Answer: Statin resumption should be individualized, weighing atherosclerotic risk against potential hemorrhagic recurrence risk

    Statin use after hemorrhagic stroke is individualized: the atherosclerotic risk-reduction benefit must be weighed against potential increased hemorrhagic recurrence risk, particularly in lobar ICH.