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Evidence-Based Stroke Protocols Flashcards

7 cards from real ASC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. According to AHA/ASA guidelines, what is the maximum acceptable door-to-CT time for acute ischemic stroke patients?

    Answer: 25 minutes

    AHA/ASA guidelines recommend a door-to-CT completion time of ≤25 minutes for acute ischemic stroke patients.

  2. Which imaging modality is considered the gold standard for detecting acute ischemic stroke within the first 24 hours?

    Answer: MRI with DWI sequence

    MRI with diffusion-weighted imaging (DWI) is the gold standard for detecting acute ischemic stroke, showing restricted diffusion within minutes of onset.

  3. In the DAWN and DEFUSE 3 trials, patient selection for late-window thrombectomy (6–24 hours) was primarily based on:

    Answer: Perfusion imaging mismatch (clinical-core or perfusion-core)

    Both DAWN and DEFUSE 3 used perfusion imaging mismatch criteria (clinical-core or perfusion-core) to identify patients with salvageable penumbra beyond 6 hours.

  4. A patient presents with acute ischemic stroke and BP of 195/105 mmHg. Per AHA guidelines, when is antihypertensive treatment indicated before IV tPA administration?

    Answer: BP ≥ 185/110 mmHg

    AHA guidelines require blood pressure to be lowered to <185/110 mmHg before administering IV alteplase to reduce hemorrhagic transformation risk.

  5. Which of the following represents the correct alteplase dosing for acute ischemic stroke?

    Answer: 0.9 mg/kg IV, max 90 mg

    The standard alteplase dose is 0.9 mg/kg (maximum 90 mg total), with 10% given as a bolus and the remaining 90% infused over 60 minutes.

  6. Per evidence-based stroke protocols, after successful IV tPA administration, when should the first post-thrombolysis CT scan be performed?

    Answer: At 24 hours post-infusion

    Standard protocols recommend a follow-up CT scan at 24 hours post-tPA to evaluate for hemorrhagic transformation before initiating antiplatelet or anticoagulant therapy.

  7. The ASPECTS (Alberta Stroke Program Early CT Score) is used to:

    Answer: Quantify early ischemic changes on non-contrast CT to guide reperfusion therapy decisions

    ASPECTS is a 10-point scoring system that quantifies early ischemic changes on non-contrast CT, with scores ≤6 generally indicating poor thrombectomy candidacy.