Evidence-Based Stroke Protocols Flashcards
7 cards from real ASC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Evidence-Based Stroke Protocols flashcards as text
According to AHA/ASA guidelines, what is the maximum acceptable door-to-CT time for acute ischemic stroke patients?
Answer: 25 minutes
AHA/ASA guidelines recommend a door-to-CT completion time of ≤25 minutes for acute ischemic stroke patients.
Which imaging modality is considered the gold standard for detecting acute ischemic stroke within the first 24 hours?
Answer: MRI with DWI sequence
MRI with diffusion-weighted imaging (DWI) is the gold standard for detecting acute ischemic stroke, showing restricted diffusion within minutes of onset.
In the DAWN and DEFUSE 3 trials, patient selection for late-window thrombectomy (6–24 hours) was primarily based on:
Answer: Perfusion imaging mismatch (clinical-core or perfusion-core)
Both DAWN and DEFUSE 3 used perfusion imaging mismatch criteria (clinical-core or perfusion-core) to identify patients with salvageable penumbra beyond 6 hours.
A patient presents with acute ischemic stroke and BP of 195/105 mmHg. Per AHA guidelines, when is antihypertensive treatment indicated before IV tPA administration?
Answer: BP ≥ 185/110 mmHg
AHA guidelines require blood pressure to be lowered to <185/110 mmHg before administering IV alteplase to reduce hemorrhagic transformation risk.
Which of the following represents the correct alteplase dosing for acute ischemic stroke?
Answer: 0.9 mg/kg IV, max 90 mg
The standard alteplase dose is 0.9 mg/kg (maximum 90 mg total), with 10% given as a bolus and the remaining 90% infused over 60 minutes.
Per evidence-based stroke protocols, after successful IV tPA administration, when should the first post-thrombolysis CT scan be performed?
Answer: At 24 hours post-infusion
Standard protocols recommend a follow-up CT scan at 24 hours post-tPA to evaluate for hemorrhagic transformation before initiating antiplatelet or anticoagulant therapy.
The ASPECTS (Alberta Stroke Program Early CT Score) is used to:
Answer: Quantify early ischemic changes on non-contrast CT to guide reperfusion therapy decisions
ASPECTS is a 10-point scoring system that quantifies early ischemic changes on non-contrast CT, with scores ≤6 generally indicating poor thrombectomy candidacy.