ASC Stroke Pharmacotherapy & Medication Management Flashcards
6 cards from real ASC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 ASC Stroke Pharmacotherapy & Medication Management flashcards as text
Which oral anticoagulant class is preferred over warfarin for secondary stroke prevention in patients with non-valvular atrial fibrillation per current AHA guidelines?
Answer: Direct oral anticoagulants (DOACs)
DOACs (apixaban, rivaroxaban, dabigatran, edoxaban) are preferred over warfarin for AF-related stroke prevention due to superior efficacy and safety profiles.
A stroke patient with atrial fibrillation and acute ischemic stroke should typically have anticoagulation initiated within what timeframe to balance stroke recurrence versus hemorrhagic transformation risk?
Answer: 4–14 days after stroke depending on infarct size
Guidelines recommend initiating anticoagulation between day 4 and 14 based on stroke severity and infarct size, balancing recurrence and bleeding risk.
Which agent is the reversal medication for dabigatran in a stroke patient with life-threatening hemorrhage?
Answer: Idarucizumab (Praxbind)
Idarucizumab is the specific reversal agent for dabigatran, a direct thrombin inhibitor, approved for emergency reversal.
Statin therapy is recommended after ischemic stroke primarily to reduce recurrence risk through which mechanism?
Answer: Plaque stabilization and LDL reduction
Statins reduce recurrent stroke risk primarily by stabilizing atherosclerotic plaque and lowering LDL cholesterol levels.
A patient with acute ischemic stroke not treated with tPA has a blood pressure of 220/120 mmHg. Per AHA guidelines, when should antihypertensive therapy be initiated?
Answer: Only if BP exceeds 220/120 mmHg persistently or symptomatic end-organ damage is present
For non-tPA patients, guidelines recommend withholding antihypertensives unless BP exceeds 220/120 or there is evidence of acute end-organ damage within the first 24–48 hours.
Which pharmacologic agent is used to treat symptomatic cerebral vasospasm following subarachnoid hemorrhage in stroke program patients?
Answer: Nimodipine
Nimodipine, an oral calcium channel blocker with selective cerebrovascular activity, is the standard pharmacologic therapy for reducing vasospasm-related neurological deficits after SAH.