APHA Special Populations & High-Risk Groups Flashcards

Which live attenuated vaccines are generally contraindicated in severely immunocompromised patients?

Answer: MMR and varicella

Live attenuated vaccines such as MMR and varicella are contraindicated in severely immunocompromised individuals because the weakened virus may replicate and cause disease.

Pregnant women are recommended to receive which vaccine during every pregnancy, ideally between 27 and 36 weeks gestation?

Answer: Tdap

Tdap is recommended during every pregnancy between 27–36 weeks gestation to protect newborns from pertussis through maternal antibody transfer.

Adults aged 65 and older should receive which pneumococcal vaccine series according to ACIP recommendations?

Answer: PCV20 alone or PCV15 followed by PPSV23

ACIP recommends adults 65+ receive either PCV20 alone or PCV15 followed by PPSV23 at least one year later for optimal pneumococcal disease protection.

Which statement is TRUE regarding influenza vaccination in individuals with egg allergy?

Answer: Persons with egg allergy of any severity can receive any age-appropriate influenza vaccine

ACIP states that persons with egg allergy of any severity can receive any licensed, recommended, age-appropriate influenza vaccine without special precautions beyond standard vaccine administration.

For preterm infants, vaccines should generally be administered based on which age parameter?

Answer: Chronological age from birth

Preterm infants should be vaccinated according to their chronological age (age since birth), not corrected gestational age, following the same recommended immunization schedule.

HIV-infected individuals who are NOT severely immunocompromised (CD4 count ≥200 cells/µL) may receive which vaccine?

Answer: MMR vaccine

MMR vaccine may be given to HIV-positive persons with CD4 counts ≥200 cells/µL who are not severely immunocompromised, as they can mount an adequate immune response.