AOCNP Survivorship and Long-Term Follow-Up 2

Question 1

A female cancer survivor treated with cyclophosphamide-based chemotherapy reports amenorrhea and hot flashes. These symptoms are most likely related to:

Accepted Answer

Premature ovarian insufficiency (POI) / chemotherapy-induced menopause

Answer

Adrenal insufficiency from chemotherapy

Answer

Hypothyroidism from radiation scatter

Answer

Paraneoplastic syndrome

Question 2

Bone health surveillance is especially critical for which category of cancer survivors?

Accepted Answer

Survivors receiving androgen deprivation therapy (ADT) or aromatase inhibitors long-term

Answer

Survivors of localized prostate cancer treated with active surveillance

Answer

Survivors of testicular cancer after orchiectomy only

Answer

Survivors who completed chemotherapy more than 10 years ago with no endocrine therapy

Question 3

Lymphedema education for breast cancer survivors should include which key preventive behaviors?

Accepted Answer

Avoid venipuncture and blood pressure measurement in the affected arm, practice skin care, and report early swelling

Answer

Avoid all exercise involving the affected arm

Answer

Wear compression garments only when flying

Answer

Restrict protein intake to reduce fluid retention

Question 4

Secondary malignancy risk is particularly elevated in survivors who received which type of treatment?

Accepted Answer

Alkylating agents and/or radiation therapy, which increase risk of therapy-related MDS/AML and solid tumors

Answer

Hormonal therapy with tamoxifen only

Answer

Anti-HER2 therapy

Answer

Immunotherapy checkpoint inhibitors

Question 5

Fertility preservation counseling is a standard of care recommendation that should be offered:

Accepted Answer

To all patients of reproductive age BEFORE initiation of potentially gonadotoxic therapy

Answer

Only to women under age 35 with hormone-sensitive cancers

Answer

Only if the patient specifically requests it

Answer

Only after treatment is complete and fertility is confirmed lost

Question 6

The primary tool used to formally screen cancer survivors for distress at regular intervals is:

Accepted Answer

The NCCN Distress Thermometer and Problem List

Answer

The PHQ-9 (Patient Health Questionnaire-9)

Answer

The Hamilton Anxiety Rating Scale

Answer

The SF-36 Health Survey