Practice Test GeeksAOA - AOA Board Certified Practice Test
← All AOA Flashcard Decks

Clinical Diagnosis and Laboratory Medicine Flashcards

7 cards from real AOA practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Clinical Diagnosis and Laboratory Medicine flashcards as text

  1. A positive tuberculin skin test (TST) with induration ≥ 5 mm is considered positive in which patient group?

    Answer: HIV-positive patients

    In immunocompromised patients such as those with HIV, a TST induration ≥5 mm is considered positive due to their increased risk of TB reactivation.

  2. Which diagnostic criterion confirms polycythemia vera according to WHO guidelines?

    Answer: JAK2 V617F mutation with elevated hemoglobin and low EPO

    WHO criteria require JAK2 V617F or exon 12 mutation plus elevated hemoglobin (>16.5g/dL men, >16g/dL women) and low serum EPO for diagnosis of polycythemia vera.

  3. Which set of laboratory values best characterizes acute pancreatitis?

    Answer: Elevated lipase >3× ULN, elevated amylase, normal LFTs

    Acute pancreatitis is diagnosed when lipase exceeds three times the upper limit of normal, often accompanied by elevated amylase; LFTs may be normal unless gallstones are involved.

  4. A patient with community-acquired pneumonia has a positive urinary antigen test. Which pathogen does this test most reliably detect?

    Answer: Legionella pneumophila serogroup 1

    The Legionella urinary antigen test specifically detects Legionella pneumophila serogroup 1, which accounts for the majority of Legionnaires' disease cases.

  5. In a patient with suspected systemic lupus erythematosus (SLE), which antibody is most specific for the diagnosis?

    Answer: Anti-double-stranded DNA (anti-dsDNA)

    Anti-dsDNA antibodies are highly specific for SLE (>95% specificity) and also correlate with disease activity and lupus nephritis.

  6. Which HbA1c value establishes a diagnosis of diabetes mellitus according to ADA criteria?

    Answer: HbA1c ≥ 6.5%

    The ADA defines diabetes as an HbA1c ≥ 6.5% confirmed on a repeat test or combined with other diagnostic criteria.

  7. A 68-year-old man has a serum PSA of 8.2 ng/mL. Which factor would most increase the suspicion for prostate cancer over benign prostatic hyperplasia (BPH)?

    Answer: Free PSA fraction of 8%

    A low free PSA fraction (<10%) suggests a higher proportion of bound PSA, which correlates with malignancy rather than the diffuse PSA release seen in BPH.